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Brazilian authorities on Wednesday approved the world's first single-dose dengue vaccine, which they hailed as a "historic" achievement as cases of the mosquito-borne disease soar globally due to rising temperatures.

Military officials in Guinea-Bissau said they had seized "total control" of the coup-prone west African country Wednesday, arresting its president, closing its borders and suspending its electoral process three days after general elections.

The Dominican Republic said Wednesday it will allow the United Sates to use an air base and airport as part of its controversial operations against alleged drug traffickers that have killed more than 80 people so far.

A surprise US plan to end the nearly four-year war in Ukraine stunned Kyiv and Europe last week, as they viewed it as echoing Russia's demands.

Two US National Guard soldiers were shot and critically wounded Wednesday two blocks from the White House and police said a suspect had been taken into custody.

President Luiz Inacio Lula da Silva said Wednesday that Brazil had given the world a lesson in democracy after his predecessor Jair Bolsonaro was jailed for a failed coup attempt.

Residents anxiously awaited news of their loved ones Thursday at a temporary shelter as one of Hong Kong's deadliest fires in decades engulfed a 2,000-unit high-rise complex.

A huge fire engulfed a crowded Hong Kong high-rise complex, killing at least 36 people and leaving more than 200 unaccounted for in the city's worst blaze in decades.

Tension is escalating between Israel's political and military top brass over accountability for the failures behind the October 7, 2023 Hamas attack, with Prime Minister Benjamin Netanyahu accused of sidestepping blame.

Military officials in Guinea-Bissau declared taking "total control" of the coup-prone west African country Wednesday, arresting its president, closing its borders and suspending its electoral process three days after general elections.

Nigeria's President Bola Tinubu on Wednesday declared a "nationwide security emergency" as the country scrambled to respond to a wave of mass kidnappings that have seen hundreds of people, mostly schoolchildren, captured in a week.

The consequences of climate change such as last year's deadly floods "increasingly threaten" the growth of Spain's economy, one of the developed world's most dynamic, the OECD warned on Wednesday.

Former England captain Lewis Moody said he had been "brought in off the bench" as he paid tribute to fellow rugby players Doddie Weir and Rob Burrow in helping raise awareness of motor neurone disease.

Food giant Campbell's has dismissed as "absurd" claims allegedly made by a senior executive, who has since been placed on leave, that its soups are made with "3D-printed" chicken and consumed by "poor people."

Hollywood actor Kevin Spacey faces another legal battle in London next year over civil sexual assault allegations, three years after he was cleared of criminal charges, a court heard Wednesday.

Formula One technical guru Adrian Newey will become Aston Martin's team principal in 2026.

A huge fire that engulfed a Hong Kong residential estate has killed at least 36 people and left more than 200 unaccounted for in the city's worst blaze in decades.

Joe Marchant will join Sale next season, the Prem club announced Wednesday, meaning the England centre will become available again for international selection ahead of the next Rugby World Cup.

As biting prices weigh on families heading into the US holiday season, farmers and business owners say President Donald Trump's tariffs have driven up production costs on everything from turkeys to vegetables.

Strasbourg defender Ben Chilwell has set his sights on delivering "the biggest middle finger" to his critics by winning a place in England's World Cup squad.

Britain's government signalled Wednesday it could issue permits for oil and gas extraction around existing North Sea fields, despite a promise to halt licences for new production in the area.

Russia said Wednesday that ongoing talks to end the war in Ukraine were "serious", after earlier welcoming parts of a new US plan to halt the deadliest fighting in Europe since World War II.

Military officers in Guinea-Bissau declared they have "total control" of the coup-prone west African country Wednesday, closing its borders and suspending its electoral process three days after general elections, with military sources confirming its president's arrest.

Britain's government unveiled a tax-raising budget Wednesday welcomed by financial markets, as its hard-hitting action aims to slash state debt as well as fund public services.

NASA has confirmed that it will contribute to Europe's Martian rover Rosalind Franklin, which is scheduled to launch in 2028 after repeated delays, the European Space Agency said on Wednesday.

Military officers in Guinea-Bissau declared "total control" of the coup-prone west African country Wednesday, closing its borders and suspending its electoral process three days after general elections.

German insurance giant Allianz signalled Wednesday looming job cuts due to its adoption of artificial intelligence with a report saying up to 1,800 roles, mainly in call centres, could be axed.

Ireland plans to curb its high population growth with sweeping new migration and asylum rules, its justice minister said Wednesday.

Newly discovered fossils prove that a mysterious foot found in Ethiopia belongs to a little-known, recently named ancient human relative who lived alongside the species of the famous Lucy, scientists said Wednesday.

A huge fire engulfed a Hong Kong residential estate and killed at least 13 people on Wednesday, with firefighters saying they were blocked from reaching some of the people seeking help.

The Swedish Energy Agency said Wednesday it was giving some $40 million in support to low-carbon steelmaker Stegra, amid fears surrounding the ambitious startup's finances.

Moldova on Wednesday displayed a Russian drone that fell on its soil outside its foreign ministry as it summoned Moscow's envoy over the crash, in an overt criticism of Russia's war in neighbouring Ukraine.