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Piastri says Japan second place 'as good as a win' for McLaren
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Nepal's former energy minister arrested in graft probe
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IOC reinstating gender tests 'a disrespect for women' - Semenya
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Youngest F1 title leader Antonelli to keep 'raising bar' after Japan win
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High hopes at China's gateway to North Korea as trains resume
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Antonelli wins in Japan to become youngest F1 championship leader
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Mercedes' Antonelli wins Japanese Grand Prix to take lead
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Germany's WWII munitions a toxic legacy on Baltic Sea floor
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Iran claims aluminium plant attacks in Gulf as Houthis join war
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North Korea's Kim oversees test of high-thrust engine: state media
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Five Apple anecdotes as iPhone maker marks 50 years
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'Excited' Buttler rejuvenated for IPL after horror T20 World Cup
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Ship insurers juggle war risks for perilous Gulf route
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Helplines buzz with alerts from seafarers trapped in war
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Let's get physical: Singapore's seniors turn to parkour
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Indian tile makers feel heat of Mideast war energy crunch
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At 50, Apple confronts its next big challenge: AI
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Houthis missile attacks on Israel widen Middle East war
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Massive protests against Trump across US on 'No Kings' day
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Struggling Force lament missed opportunities after Chiefs defeat
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Lakers guard Doncic gets one-game ban for accumulated technicals
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Houthis claim missile attacks on Israel, entering Middle East war
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NBA Spurs stretch win streak to eight in rout of Bucks
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US lose 5-2 to Belgium in rude awakening for World Cup hosts
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Sabalenka sinks Gauff to win second straight Miami Open title
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Lebanon kids struggle to keep up studies as war slams school doors shut
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Cherry blossoms, kite-flying and 'No Kings' converge on Washington
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Britain's Kerr to target El Guerrouj's mile world record
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Sailboats carrying aid reach Cuba after going missing: AFP journalist
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Pakistan to host Saudi, Turkey, Egypt for talks on Mideast war
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Formidable Sinner faces Lehecka for second Miami Open title
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Tuchel plays down Maguire's World Cup hopes
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'Risky moment': Ukraine treads tightrope with Gulf arms deals
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Japan strike late to win Scotland friendly
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India great Ashwin joining San Francisco T20 franchise
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Israel hits Iran naval research site, fresh blasts rattle Tehran
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Kohli fires Bengaluru to big win after IPL remembers stampede dead
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Graou shines as Toulouse sink Montpellier, Pau climb to second in Top 14
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Vingegaard nears Tour of Catalonia victory with stage six win
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Malinin bounces back from Olympic meltdown with third straight world skating gold
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French police foil Paris bomb attack outside US bank
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Senegal parade AFCON trophy at Stade de France, despite being stripped of title
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Graou shines as Toulouse sink Montpellier to extend Top 14 lead
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Anti-Trump protests launch on 'No Kings' day in US
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Protesters rally in London against UK far-right rise
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France foils Paris bomb attack outside US bank
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Indian Premier League cricket season begins with silence to honour stampede dead
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Missing Cuba-bound aid boats located, crew reported safe
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Ignore our celebrations, we respect Bosnian team, says Italy's Dimarco
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Case closed for Morocco despite Senegal Afcon outrage
Stocks slide as investors await key Fed speech
Stock markets mostly fell during cautious trading sessions Thursday, a day before a key speech expected to offer signals about future interest rate cuts in the United States.
US Federal Reserve Chairman Jerome Powell, who has resisted President Donald Trump's public demands to slash rates, is scheduled to deliver remarks Friday at the annual central bankers conference in Wyoming.
Major European indices were lower in midday trading, tracking a lacklustre session in Asia, and Wall Street indices opened lower after weakness seen on Wednesday.
Investors largely brushed off purchasing managers' index (PMI) data showing eurozone business activity reached a 15-month high in August, while UK activity grew at its fastest pace in a year.
"Eyes are turning to... Powell's final speech at the Jackson Hole Symposium as Federal Reserve Chair (before his term ends in May 2026)," said Susannah Streeter, head of money and markets at Hargreaves Lansdown.
"Although the effect of Trump's tariffs on monetary policy will be the undercurrent theme, investors will be looking specifically for clues as to the Fed's inclination to cut interest rates," she said.
Data last week provided a mixed picture of US inflation, leaving it uncertain whether the Fed will lower rates as many investors expect in September -- a move that could bolster growth in the world's largest economy.
A recent sell-off in major tech stocks has added to market uncertainty, as investors grow wary of the sustained rally across the sector since April.
The tech-heavy Nasdaq fell again on Thursday, though shares in AI chip designer Nvidia were trading flat after heavy selling in previous sessions ahead of its earnings report next week.
Despite the building unease, shares in Seoul closed higher Thursday, bolstered by an uptick in Samsung's share price.
Shanghai, Sydney and Taipei also saw moderate gains.
Tokyo's Nikkei index closed lower, along with Hong Kong.
Global markets have also fluctuated recently on the prospects of a peace deal in Ukraine, following days of high-stakes diplomacy in the aftermath of Trump's Friday meeting with Russian counterpart Vladimir Putin.
The diplomatic whirlwind has sparked volatility in oil markets as traders speculate over the possible lifting of sanctions on Russia, a major producer.
Oil prices rose again Thursday, following a report the previous day showing a sharp decline in US crude stockpiles.
- Key figures at around 1340 GMT -
New York - Dow: DOWN 0.6 percent at 44,675.02 points
New York - S&P 500: DOWN 0.3 percent at 6,374.53
New York - Nasdaq: DOWN 0.3 percent at 21,116.06
London - FTSE 100: DOWN 0.3 percent at 9,259.45 points
Paris - CAC 40: DOWN 0.6 percent at 7,293.03
Frankfurt - DAX: DOWN 0.2 percent at 24,227.68
Tokyo - Nikkei 225: DOWN 0.7 percent at 42,610.17 (close)
Hong Kong - Hang Seng Index: DOWN 0.2 percent at 25,104.61 (close)
Shanghai - Composite: UP 0.1 percent at 3,770.78 (close)
Euro/dollar: DOWN at $1.1639 from $1.1648 on Wednesday
Pound/dollar: DOWN at $1.3441 from $1.3452
Dollar/yen: UP at 147.64 yen from 147.44 yen
Euro/pound: DOWN at 86.56 pence from 86.59 pence
West Texas Intermediate: UP 0.1 percent at $63.28 per barrel
Brent North Sea Crude: UP 0.1 percent at $66.93 per barrel
P.Mira--PC