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American Nobel laureate in medicine hopes to illuminate the brain
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Tens of thousands expected in Paris for high school protests
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Trump approves firing squad for convicted US military base shooter
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AI borrowing binge rattles US markets
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Grappling with 'homework scams,' US universities shun AI detectors
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Young Canadians sue government over alleged climate failures
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Separatists win Quebec election in test for Canada PM
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White Sox down Guardians to take 2-0 series lead
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Leaders visit Pacific atoll at frontline of climate change
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NHL record-breaker Ovechkin says current season will be his last
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Yemen's Houthis claim striking Riyadh airport, other Saudi sites
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France roar back in Nations League as Italy beat Turkey
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Best-selling British author Jeffrey Archer dies aged 86
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Messi readies for final farewell in Argentina send-off
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Military plane crash kills 32 in Nigeria
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Esposito seals Italy win over Turkey in Nations League
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Olise powers France to win over Belgium in Nations League
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Russia downplays plague reports as Trump offers US help
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High-flying Blazy turns to birdlife at Chanel
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Trump says US moved bombers from UK base after 'threats'
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Riyadh's allies pledge troops as Yemen, Saudi Arabia attack Houthis
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Brazilian stocks surge to record after Bolsonaro election lead
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Clashes erupt outside Kosovo parliament over war crimes court
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Leaders to visit Pacific atoll at frontline of climate change
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Milan's Saelemaekers suffers ankle setback, faces lengthy spell out
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ICC gives more details about arrest warrants for Taliban ministers
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Rubio arrives in Iceland to push for greater US presence in Arctic
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Nigeria's Tinubu confirms 32 dead after military plane crash
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Putin allows Italy's UniCredit to sell part of Russian business
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'Reckless' AI firms can't control models, says whistleblower
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Djokovic into China Open final as Medvedev out for hitting fan with ball
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Switching on brain cells: the Nobel-winning science of optogenetics
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ICC unseals arrest warrants for Taliban education ministers
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Quebec votes as separatist surge poses test for Canada PM
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Modric hopes fans back Croatia against Spain after England shame
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Euro slides as concerns about French debt mount
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Bolsonaro rides right-wing surge into Brazil's election runoff
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Former Trump press secretary Leavitt joins Fox News
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Turkey blocks X account of British reporter
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Djokovic advances to China Open final as Medvedev out for hitting fan with ball
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Ukraine says using AI robot guns to shoot down new Russian drones
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Disgraced former US House speaker dies at 84
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At Oct 7 memorial, Netanyahu says will be no Hamas rule in Gaza
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Euro slides as worries about French debt grow
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Ukraine blames Russia for deadly sinking of Turkish ship in Black Sea
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US withdraws all bomber aircraft from UK airbase
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UN rights council slams Taliban's 'oppression' of women
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Drone hits Ethiopia IDP camp as fears grow of regional war
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Norway eyes partial ban of smart glasses
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US-German trio wins medicine Nobel for illuminating the brain
Stock markets diverge tracking US outlook
Europe's main stock markets dropped Tuesday after gains for Chinese indices, as traders sought to ascertain the outlook for US interest rates ahead of the presidential election.
Investor focus was also on company earnings, as gold and oil prices continued to win support from Middle East tensions.
"A mix of continuing unrest in the Middle East and uncertainty over the US election casts a cautious shadow over markets," noted Derren Nathan, head of equity research at Hargreaves Lansdown.
Wall Street retreated from record highs Monday, while the dollar was mixed against main rivals on Tuesday.
Tech titans Alphabet and IBM announce their latest results over the next two days, while earnings from Boeing, Coca-Cola, and L'Oreal are also in the pipeline.
General Motors raised some of its full-year profit projections Tuesday following solid earnings as strong vehicle pricing compensated for lower auto sales.
All major European equity markets were in the red mid-session Tuesday, after gains for Shanghai and Hong Kong in the hope of more Chinese stimulus.
London stocks fell following data that showed UK public borrowing rose more than expected in September, as the new Labour government prepares for its first budget next week that is expected to include tax rises.
Frankfurt edged lower but was bolstered by strong third-quarter earnings for German software giant SAP, whose shares were up nearly four percent in early afternoon deals.
Expectations of another bumper US interest-rate cut from the Federal Reserve have been tempered slightly following a recent run of strong American data on jobs creation and as some top decision-makers suggested they would like to see a slower pace of rate cuts.
Concerns over the outcome of the US election on November 5 have weighed on investor sentiment, with general consensus across polls and forecasts being that Donald Trump has "gained ground" on Kamala Harris, Deutsche Bank economists noted.
Tokyo closed down more than one percent Tuesday, even as the yen softened against the dollar to sit at its weakest level since early August.
Gold hit a fresh record high at $2,740.59 an ounce, as traders sought out the haven investment as Israel considers its response to Iran's missile barrage this month.
Uncertainty over the US presidential election has also helped fuel the precious metal's rally, according to analysts who added that concerns about a possible wider conflict in the Middle East were lifting oil prices.
- Key figures around 1045 GMT -
London - FTSE 100: DOWN 0.7 percent at 8,318.24 points
Paris - CAC 40: DOWN 0.8 percent at 7,480.06
Frankfurt - DAX: DOWN 0.4 percent at 19,389.96
Tokyo - Nikkei 225: DOWN 1.4 percent at 38,411.96 (close)
Hong Kong - Hang Seng Index: UP 0.1 percent at 20,498.95 (close)
Shanghai - Composite: UP 0.5 percent at 3,285.87 (close)
New York - Dow: DOWN 0.8 percent at 42,931.60 (close)
Euro/dollar: UP at $1.0826 from $1.0818 on Monday
Pound/dollar: DOWN at $1.2977 from $1.2982
Dollar/yen: UP at 150.86 yen from 150.82 yen
Euro/pound: UP at 83.41 pence from 83.30 pence
Brent North Sea Crude: UP 0.9 percent at $74.95 per barrel
West Texas Intermediate: UP 1.0 percent at $70.72 per barrel
A.Aguiar--PC